銠(I)金屬催化烯基硼酸試劑對α,β-不飽和酮類化合物的不對稱1,4-加成反應

dc.contributor吳學亮zh_TW
dc.contributorHsyueh-Liang Wuen_US
dc.contributor.author廖柏翔zh_TW
dc.contributor.authorLiao, Bo-Xiangen_US
dc.date.accessioned2019-09-04T09:28:17Z
dc.date.available2019-7-2
dc.date.available2019-09-04T09:28:17Z
dc.date.issued2014
dc.description.abstract本論文是利用一價銠金屬和掌性樟腦型雙環[2.2.1]雙烯配基(25A)作為催化基,催化烯基硼酸試劑與α,β-不飽和酮類化合物進行不對稱1,4加成反應,利用各種不同的烯基硼酸試劑及α,β-不飽和酮類化合物合成出一系列β-烯基取代酮化合物。這些產物都具有很好的產率以及高的立體選擇性,產率最高可達99%,而鏡像超越值可高達>99.5% ee。zh_TW
dc.description.abstractAn efficient enantioselective conjugate addition of alkenylboronic acids to α,β-unsaturated carbonyl compounds was realized. In the presence of 1 mol% of rhodium catalyst in situ prepared from [RhCl(C2H4)2]2 and ligand 25A, conjugation addition of various alkenylboronic acids to α,β-unsaturated carbonyl compounds furnishes the desired adducts in high yields (up to 99%) and in up to >99.5% ee.en_US
dc.description.sponsorship化學系zh_TW
dc.identifierGN060142082S
dc.identifier.urihttp://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN060142082S%22.&%22.id.&
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100459
dc.language中文
dc.subject銠金屬zh_TW
dc.subject烯基硼酸試劑zh_TW
dc.subjectαzh_TW
dc.subjectβ-不飽和酮類化合物zh_TW
dc.subject不對稱1zh_TW
dc.subject4加成反應zh_TW
dc.subject立體選擇性zh_TW
dc.subject鏡像超越值zh_TW
dc.subjectRhodiumen_US
dc.subjectalkenylboronic acidsen_US
dc.subjectαen_US
dc.subjectβ-unsaturated carbonyl compoundsen_US
dc.subjectasymmetric conjugation additionen_US
dc.subjectenantioselectiveen_US
dc.subjecteeen_US
dc.title銠(I)金屬催化烯基硼酸試劑對α,β-不飽和酮類化合物的不對稱1,4-加成反應zh_TW
dc.titleRhodium-Catalyzed Asymmetric 1,4-addition of Alkenylboronic acids to α,β-Unsaturated Carbonyl Compoundsen_US

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