銠(I)金屬催化烯基硼酸試劑對α,β-不飽和酮類化合物的不對稱1,4-加成反應 Rhodium-Catalyzed Asymmetric 1,4-addition of Alkenylboronic acids to α,β-Unsaturated Carbonyl Compounds

dc.contributor 吳學亮 zh_TW
dc.contributor Hsyueh-Liang Wu en_US
dc.contributor.author 廖柏翔 zh_TW
dc.contributor.author Liao, Bo-Xiang en_US
dc.date.accessioned 2019-09-04T09:28:17Z
dc.date.available 2019-7-2
dc.date.available 2019-09-04T09:28:17Z
dc.date.issued 2014
dc.description.abstract 本論文是利用一價銠金屬和掌性樟腦型雙環[2.2.1]雙烯配基(25A)作為催化基,催化烯基硼酸試劑與α,β-不飽和酮類化合物進行不對稱1,4加成反應,利用各種不同的烯基硼酸試劑及α,β-不飽和酮類化合物合成出一系列β-烯基取代酮化合物。這些產物都具有很好的產率以及高的立體選擇性,產率最高可達99%,而鏡像超越值可高達>99.5% ee。 zh_TW
dc.description.abstract An efficient enantioselective conjugate addition of alkenylboronic acids to α,β-unsaturated carbonyl compounds was realized. In the presence of 1 mol% of rhodium catalyst in situ prepared from [RhCl(C2H4)2]2 and ligand 25A, conjugation addition of various alkenylboronic acids to α,β-unsaturated carbonyl compounds furnishes the desired adducts in high yields (up to 99%) and in up to >99.5% ee. en_US
dc.description.sponsorship 化學系 zh_TW
dc.identifier GN060142082S
dc.identifier.uri http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN060142082S%22.&%22.id.&
dc.identifier.uri http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100459
dc.language 中文
dc.subject 銠金屬 zh_TW
dc.subject 烯基硼酸試劑 zh_TW
dc.subject α zh_TW
dc.subject β-不飽和酮類化合物 zh_TW
dc.subject 不對稱1 zh_TW
dc.subject 4加成反應 zh_TW
dc.subject 立體選擇性 zh_TW
dc.subject 鏡像超越值 zh_TW
dc.subject Rhodium en_US
dc.subject alkenylboronic acids en_US
dc.subject α en_US
dc.subject β-unsaturated carbonyl compounds en_US
dc.subject asymmetric conjugation addition en_US
dc.subject enantioselective en_US
dc.subject ee en_US
dc.title 銠(I)金屬催化烯基硼酸試劑對α,β-不飽和酮類化合物的不對稱1,4-加成反應 zh_TW
dc.title Rhodium-Catalyzed Asymmetric 1,4-addition of Alkenylboronic acids to α,β-Unsaturated Carbonyl Compounds en_US
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