製備金奈米複合載體及利用近紅外光雷射控制其在藥物傳輸之應用
| dc.contributor | 陳家俊 | zh_TW |
| dc.contributor | Chia-Chun Chen | en_US |
| dc.contributor.author | 趙育慶 | zh_TW |
| dc.contributor.author | Yu-Ching Chao | en_US |
| dc.date.accessioned | 2019-09-04T09:44:20Z | |
| dc.date.available | 不公開 | |
| dc.date.available | 2019-09-04T09:44:20Z | |
| dc.date.issued | 2008 | |
| dc.description.abstract | 本文是製備包覆多層高分子之金奈米棒（GNRs-MLP）來作為藥物載體。我們將包覆 paclitaxel 的金奈米複合材料載體加入人類乳癌細胞 MCF-7 中，再以近紅外光飛秒雷射照射，會發現細胞的增殖受到藥物抑制，由 MTT assay 結果證實 paclitaxel 也可經由這種機制釋放出來。因此我們認為這種金奈米複合材料載體在藥物傳輸上極具潛力。 | zh_TW |
| dc.description.abstract | In this work, we have been prepared gold nanorods coated with polymer as drug reservoirs. We found that when the drug carriers were exposed to femto-second NIR, the multilayer structure was expanded and paclitaxel was released. After the drug carriers were added to MCF-7 cells, MTT assay shows that the drug carriers combined with NIR irradiation allow the induction of paclitaxel in MCF-7 cells and inhibit the cell growth. We think the gold nanocomposites as nanocarriers have potentiality in drug delivery. | en_US |
| dc.description.sponsorship | 化學系 | zh_TW |
| dc.identifier | GN0695420316 | |
| dc.identifier.uri | http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN0695420316%22.&%22.id.& | |
| dc.identifier.uri | http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100636 | |
| dc.language | 中文 | |
| dc.subject | 金奈米複合載體 | zh_TW |
| dc.subject | 藥物傳輸 | zh_TW |
| dc.title | 製備金奈米複合載體及利用近紅外光雷射控制其在藥物傳輸之應用 | zh_TW |
| dc.title | Preparation of Gold Nanocomposites as Drug Carriers and Their Application in the Release of Drug Triggering by Near-infrared Laser | en_US |