利用有機不對稱催化建構具有多取代的環己酮衍生物
| dc.contributor | 林文偉 | zh_TW |
| dc.contributor | wen-wei, Lin | en_US |
| dc.contributor.author | 陳錡翰 | zh_TW |
| dc.contributor.author | chi-han, Chen | en_US |
| dc.date.accessioned | 2019-09-04T09:20:59Z | |
| dc.date.available | 不公開 | |
| dc.date.available | 2019-09-04T09:20:59Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | a,b-不飽和-1,3-雙酮和亞烷基丙二腈為起始物透過奎寧進行連續性的二次 Michael 加成反應，得到具有兩個立體中心的多取代環己酮衍生物，產率為 59-94%、單一非鏡像異構物和高達 92% 的鏡像超越值。 | zh_TW |
| dc.description.abstract | organocatalytic asymmetric double Michael addition reaction of a,b-unsaturated-1,3-diketones to 2-alkylidene malononitriles 80 has been investigated with quinine as the catalyst to afford a range of multi-substituted cyclohexanones bearing two sterecenters in good results (58-94% yield, >99:1 de, and up to 92% ee). | en_US |
| dc.description.sponsorship | 化學系 | zh_TW |
| dc.identifier | GN060042053S | |
| dc.identifier.uri | http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN060042053S%22.&%22.id.& | |
| dc.identifier.uri | http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100365 | |
| dc.language | 中文 | |
| dc.subject | 連續性反應 | zh_TW |
| dc.subject | 環己酮 | zh_TW |
| dc.subject | 鏡像選擇性 | zh_TW |
| dc.subject | Domino reaction | en_US |
| dc.subject | Cyclohexanone | en_US |
| dc.subject | Enantioselectivity | en_US |
| dc.title | 利用有機不對稱催化建構具有多取代的環己酮衍生物 | zh_TW |
| dc.title | Enantioselective synthesis of multi-substituted cyclohexanone derivatives via organocatalytic asymmetric double michael addition | en_US |