手性硫化物於催化性氮丙啶化反應之應用
(Thiolan-2-yl)diphenylmethanol-catalyzed asymmetric aziridination
手性硫化物於催化性氮丙啶化反應之應用
(Thiolan-2-yl)diphenylmethanol-catalyzed asymmetric aziridination
Date
2013
Authors
黃孟婷
Huang, Meng-Ting
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Abstract
以市售的5-溴基戊酸乙脂作為起始物，經由四步驟合成而得硫化物1b-1d，接著再一步驟得到硫化物衍生物2b-2d。接著，以硫化物2b-2d作為催化劑進行不對稱氮丙啶反應之應用。
A novel chiral tetrahydrothiophene derivative 2b-2d was obtained from commercially available 5-Bromovalerate through a 5-steps synthetic route. We demonstrated the application of catalytic and asymmetric process for aziridination mediated by sulfur ylides.
A novel chiral tetrahydrothiophene derivative 2b-2d was obtained from commercially available 5-Bromovalerate through a 5-steps synthetic route. We demonstrated the application of catalytic and asymmetric process for aziridination mediated by sulfur ylides.
Description
Keywords
鋶偶極體,
亞胺,
氮丙啶,
立體選擇性反應,
有機催化劑,
sulfur-ylide,
N-diphenylphosphinic imine,
diaryl aziridine,
enantioselective reaction,
organocatalyst