吩噻嗪化合物之氧化聚合與偶氮化聚合對修飾電位之關係

Abstract

有鑒於吩噻嗪化合物具有與核黃素相似的吩噻嗪結構，本研究於是以循環伏安法(CV)以及原子力顯微鏡(AFM) 探討 phenothiazine 化合物之電化學性質。過程中利用循環伏安法將 Thionine Chloride(TC) 、 Toluidine Blue (TB)、Methylene Blue (MB)等 Phenothiazine 類化合物氧化聚合及偶氮化還原聚合在 ITO 及 HOPG 表面，並藉此探討修飾電位的影響性，且利用刮除法得知修飾物厚度，最終以終端電位及修飾物厚度來找出修飾及固定用的吩噻嗪化合物。未來在如製作生化感測器上等時我們能得知要用何種吩噻嗪化合物及修飾方法來固定其效果為最好。In view of the structural similarity of the thiophene of phenothiazine compounds and riboflavin, the electrochemical properties of phenothiazine compounds are studied by Cyclic Voltammetry (CV) and Atomic Force Microscopy (AFM). Cyclic Voltammetry is used to explore the effects of modified potential of Thionine Chloride (TC), Toluidine Blue (TB), Methylene Blue (MB) and other phenothiazine compounds oxidation polymerization and azo-reduction polymerization on ITO and HOPG surface, finally, the scraping method is used to determine the thickness of the modifier, then use thickness of the modifier and final potential to determinate use what kind of phenothiazine compounds to modify and immobile. In the feature we can know what kind of phenothiazine compound is the best to used immobile and what kind of modify method in making such as biosensor as so on.