1.三氯化鐵輔佐之環化反應：多氫吲哚與雙環[2.2.2]辛-2-烯衍生物的合成 2.金(I)催化3-(3-苯基丙炔胺基)環己-2-烯-1-酮的環化反應：二氫喹啉酮衍生物的合成

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dc.contributor葉名倉zh_TW
dc.contributorMing-Chang Yehen_US
dc.contributor.author江孟潔zh_TW
dc.contributor.authorMeng-Jie Jiangen_US
dc.date.accessioned2019-09-04T09:20:06Z
dc.date.available2018-7-31
dc.date.available2019-09-04T09:20:06Z
dc.date.issued2013
dc.description.abstract研究主要分成三個部份，第一個部份是利用三氯化鐵輔佐反式4-(3- 芳香基丙炔(對甲苯磺醯基)胺基)環己-2-烯-1-醇進行環化反應，在室溫、空 氣下進行反應得到氯化多氫吲哚衍生物。第二部分是以三氯化鐵輔佐4-(3- 芳香基丙炔基)環己-2-烯-1-醇行環化反應得到氯化雙環[2.2.2]辛烯衍生物， 此環化反應中，三氯化鐵同時當作路易士酸和氯離子的來源。第三部分利 用金(I)催化3-(3-苯基丙炔胺基)環己-2-烯-1-酮行6-endo-dig 環化反應得到 二氫喹啉酮結構。zh_TW
dc.description.abstractThere are three parts in this study. The first work is the simple and efficient FeCl3-promoted cyclization/chlorination of trans 4-(3-arylpropargyl tosyl-amino)cyclohex-2-en-1-ols. The reaction proceeded at room temperature in air to afford multi-hydroindoles. Second part of this thesis describes the synthesis of bicyclo[2.2.2]oct-2-ene from 4-(3-arylpropargyl)cyclohex-2-en-1- ols using FeCl3. In this reaction, FeCl3 reacts as both Lewis acid and the chloride source for the cyclization/chlorination. Finally, a method to construct the dihydroquinolinone skeleton from 3-(3-phenylpropargylamino)cyclohex- 2-en-1-ones by a Au(I)-catalyzed 6-endo-dig cycloisomerization was developed.en_US
dc.description.sponsorship化學系zh_TW
dc.identifierGN060042035S
dc.identifier.urihttp://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22GN060042035S%22.&%22.id.&
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100352
dc.language中文
dc.subject三氯化鐵zh_TW
dc.subject多氫吲哚衍生物zh_TW
dc.subject雙環[2.2.2]辛烯衍生物zh_TW
dc.subject金zh_TW
dc.subject二氫喹啉酮zh_TW
dc.subjectFeCl3en_US
dc.subjectmulti-hydroindolesen_US
dc.subjectbicyclo[2.2.2]oct-2-eneen_US
dc.subjectgolden_US
dc.subjectdihydroquinolinoneen_US
dc.title1.三氯化鐵輔佐之環化反應：多氫吲哚與雙環[2.2.2]辛-2-烯衍生物的合成 2.金(I)催化3-(3-苯基丙炔胺基)環己-2-烯-1-酮的環化反應：二氫喹啉酮衍生物的合成zh_TW
dc.title1.FeCl3-Promoted Intramolecular Cyclization Reactions：Syntheses of Perhydroindoles and Bicyclo[2.2.2]oct-2-enes 2.Gold(I)-Catalyzed Cycloisomerization Reactions of 3-(3-Phenylpropargylamino)cyclohex-2-en-1-ones : Synthesis of Dihydroquinolinonesen_US

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