一鍋多組份合成α-四氫吡咯苯烷酮類新興濫用物質與氣相層析質譜分析

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dc.contributor姚清發zh_TW
dc.contributorYao, Ching-Faen_US
dc.contributor.author邱冠維zh_TW
dc.contributor.authorChiu, Kuan-Weien_US
dc.date.accessioned2019-09-04T09:09:49Z
dc.date.available2018-01-28
dc.date.available2019-09-04T09:09:49Z
dc.date.issued2018
dc.description.abstract本論文探討以三步驟合成新興濫用物質α-四氫吡咯苯烷酮衍生物及其分析，利用條件溫和且易取得之化學原料，以佛瑞德-克來福特醯化反應，讓起始物一次與六種烷基醯氯進行反應、再經過α-溴化及胺化反應後，迅速合成出六種α-四氫吡咯苯烷酮之衍生物，並透過改變起始物合成出一系列之衍生物，所得產物再以氣相層析質譜儀進行分析，建立起此類新興濫用物質及其中間產物的標準圖譜。 關鍵字(詞)：新興精神活性物質、α-四氫吡咯苯烷酮類、氣相層析質譜分析zh_TW
dc.description.abstractThis essay focuses on the one-pot multi-component synthesis of α-pyrrolidinophenones. Using a three steps process. The starting material and six types of alky acyl chloride undergo Friedel-Crafts acylation, α-bromination and amination reactions. This process swiftly synthesis six types of α-pyrrolidinophenones and its intermediate products, then by changing the starting material can get different derivatives. All products are then analyzed via gas chromatography–mass spectrometry to establish a complete mass spectrum database. Keywords：Novel Psychoactive Substances, α-Pyrrolidinophenones, Gas Chromatography–Mass Spectrometryen_US
dc.description.sponsorship化學系zh_TW
dc.identifierG060442068S
dc.identifier.urihttp://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22G060442068S%22.&%22.id.&
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100139
dc.language中文
dc.subject新興精神活性物質zh_TW
dc.subjectα-四氫吡咯苯烷酮類zh_TW
dc.subject氣相層析質譜分析zh_TW
dc.subjectNovel Psychoactive Substancesen_US
dc.subjectα-Pyrrolidinophenonesen_US
dc.subjectGas Chromatography–Mass Spectrometryen_US
dc.title一鍋多組份合成α-四氫吡咯苯烷酮類新興濫用物質與氣相層析質譜分析zh_TW
dc.titleOne-pot Multi-component Synthesis of α-Pyrrolidinophenones and Analysis via Gas Chromatography–Mass Spectrometryen_US

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