利用區域選擇開關反應合成異喹啉酮和羥基異吲哚啉酮的衍生物以及利用銅催化合成苯並咪唑喹唑啉酮的衍生物
| dc.contributor | 姚清發 | zh_TW |
| dc.contributor | Yao, Ching-Fa | en_US |
| dc.contributor.author | 何師辰 | zh_TW |
| dc.contributor.author | Ho, Shih-Chen | en_US |
| dc.date.accessioned | 2019-09-04T09:08:31Z | |
| dc.date.available | 不公開 | |
| dc.date.available | 2019-09-04T09:08:31Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | 本論文主要分為兩個章節。 第壹章節先簡單定義什麼是區域選擇開關反應和文獻回顧，並介紹實驗室的學長們過去所做的研究，進而決定研究方向，以銅金屬和鹼做區域選擇開關反應，可以合成出羥基異吲哚啉酮的衍生物，亦可合成出吲哚異喹啉酮的衍生物 第貳章節先介紹喹唑啉酮和苯並咪唑這兩種具有生物活性的架構，做文獻回顧，並且以銅當作催化劑，進而合成出苯並咪唑喹唑啉酮的衍生物。 | zh_TW |
| dc.description.abstract | This thesis is divided into two chapters. The first chapter is definition, that is, the regioselective switching reaction. First, we briefly define the meaning of regioselective switching reaction, and review literatures about regioselective switching reaction in recent years. Secondly, we introduce the studies done by the seniors in our laboratory and determine our goal. In the reaction, we use copper and base as our switch. Finally, we use this kind of switch to synthesize the derivatives of hydroxy isoindolinone and isoquinolinone. In the second chapter, we will introduce the bioactivities of quinazolinone and benzimidazole. Then, we will review some literatures, and confirm our goal. We use copper as our catalyst in the experiment, and synthesize the benzimidazoquinazolinone derivatives. | en_US |
| dc.description.sponsorship | 化學系 | zh_TW |
| dc.identifier | G060442007S | |
| dc.identifier.uri | http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22G060442007S%22.&%22.id.& | |
| dc.identifier.uri | http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100100 | |
| dc.language | 中文 | |
| dc.subject | 羥基異吲哚啉酮 | zh_TW |
| dc.subject | 吲哚異喹啉酮 | zh_TW |
| dc.subject | 苯並咪唑喹唑啉酮 | zh_TW |
| dc.subject | hydroxy isoindolinone | en_US |
| dc.subject | isoquinolinone | en_US |
| dc.subject | benzimidazoquinazolinone | en_US |
| dc.title | 利用區域選擇開關反應合成異喹啉酮和羥基異吲哚啉酮的衍生物以及利用銅催化合成苯並咪唑喹唑啉酮的衍生物 | zh_TW |
| dc.title | Regioselective Switching Reactions for the Synthesis of Indoloisoquinoline and Hyroxyisoindolone Derivatives and Copper Catalyze Synthesis of Benzoimidazoquinazolinone Derivatives | en_US |