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Title: Oleic acid-enhanced transdermal delivery pathways of fluorescent nanoparticles
Authors: 國立臺灣師範大學化學系
W. Lo
A. Ghazaryan
C.-H. Tso
P.-S. Hu
W.-L. Chen
T.-R. Kuo
S.-J. Lin
S.-J. Chen
Chia-Chun Chen
C.-Y. Dong
Issue Date: 21-May-2012
Publisher: American Institute of Physics (AIP)
Abstract: Transdermal delivery of nanocarriers provides an alternative pathway to transporttherapeutic agents, alleviating pain, improving compliance of patients, and increasing overall effectiveness of delivery. In this work, enhancement of transdermal delivery of fluorescent nanoparticles and sulforhodamine B with assistance of oleic acid was visualized utilizing multiphoton microscopy (MPM) and analyzed quantitatively using multi-photon excitation-induced fluorescent signals. Results of MPM imaging and MPM intensity-based spatial depth-dependent analysis showed that oleic acid is effective in facilitating transdermal delivery of nanoparticles.
ISSN: 0003-6951
Other Identifiers: ntnulib_tp_C0301_01_082
Appears in Collections:教師著作

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