屏面掃描式三維光學同調斷層造影系統之設計與架設
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2007
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Abstract
光學同調斷層攝影術(Optical Coherence Tomography；OCT)是一種基於低同調干涉儀原理的造影技術，自1991年被提出以來，已經成為一個能提供非接觸式與高速斷層影像的有利工具。藉由搭配寬頻近紅外光源的使用，OCT可在數釐米的穿透深度範圍內具有10到30微米的空間解析力。在本研究中，我們設計並架設一套屏面掃描式三維光學同調斷層造影系統:以超高亮度發光二極體為光源，搭配聲光調變器產生並偵測外差干涉訊號。以此自行建立的架構下，我們可以高速掃描鏡子產生大面積屏面掃描影像，最後藉由多張二維屏片影像重組出三維立體影像，可用來完整描述待測物體的結構而不會遺漏掉任何有用的資訊。
Since its introduction in 1991, optical coherence tomography (OCT), based on low coherence interferometry, has been used as a powerful tool to support non-contact and high-speed tomographic images. By using broadband near-infrared light sources, OCT achieves resolutions of 10 to 30 m with depth penetrations of the order of a few milimeters. In this research, we designed and construct an en-face three-dimensional (3D) OCT system: a superluminescent diode is used as a light source in combination with acousto-optic modulators for heterodyne signal generation and detection. With our setup we are able to scan en-face areas by using a resonant scanning mirror. After reconstruction of several 2D sections, 3D OCT image can fully describe the 3D morphology of samples under study, no structural details are missed.
Since its introduction in 1991, optical coherence tomography (OCT), based on low coherence interferometry, has been used as a powerful tool to support non-contact and high-speed tomographic images. By using broadband near-infrared light sources, OCT achieves resolutions of 10 to 30 m with depth penetrations of the order of a few milimeters. In this research, we designed and construct an en-face three-dimensional (3D) OCT system: a superluminescent diode is used as a light source in combination with acousto-optic modulators for heterodyne signal generation and detection. With our setup we are able to scan en-face areas by using a resonant scanning mirror. After reconstruction of several 2D sections, 3D OCT image can fully describe the 3D morphology of samples under study, no structural details are missed.
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Keywords
屏面掃描, 三維光學同調, en-face, OCT