Selective Binding of Mannose-Encapsulated Gold Nanoparticles to Type I Pili in Escherichia Coli
| dc.contributor | 國立臺灣師範大學化學系 | zh_tw |
| dc.contributor.author | C.-C. Lin | en_US |
| dc.contributor.author | Y.-C. Yeh | en_US |
| dc.contributor.author | C.-Y. Yang | en_US |
| dc.contributor.author | C.-L. Chen | en_US |
| dc.contributor.author | G.-F. Chen | en_US |
| dc.contributor.author | Chia-Chun Chen | en_US |
| dc.contributor.author | Y.-C. Wu | en_US |
| dc.date.accessioned | 2014-12-02T06:41:30Z | |
| dc.date.available | 2014-12-02T06:41:30Z | |
| dc.date.issued | 2002-04-10 | zh_TW |
| dc.description.abstract | The synthesis, characterization and biological application of mannose encapsulated gold nanoparticles (m-AuNP) are reported. m-AuNP is well dispersed and very stable without aggregation in the media of broad ion strength and pH ranges. The selective binding of m-AuNP to the mannose adhesin FimH of bacterial type 1 pili is demonstrated using transmission electron microscopy. The competition assay with free mannose suggests that m-AuNP binds FimH better than free mannose does. This work demonstrates that carbohydrate attached nanoparticles can be used as an efficient affinity label and a multi-ligand carrier in a biological system. | en_US |
| dc.description.uri | http://pubs.acs.org/doi/pdf/10.1021/ja0200903 | zh_TW |
| dc.identifier | ntnulib_tp_C0301_01_010 | zh_TW |
| dc.identifier.issn | 0002-7863 | zh_TW |
| dc.identifier.uri | http://rportal.lib.ntnu.edu.tw/handle/20.500.12235/42294 | |
| dc.language | en_US | zh_TW |
| dc.publisher | American Chemical Society | en_US |
| dc.relation | Journal of the American Chemical Society, 124(14), 3508-3509. | en_US |
| dc.relation.uri | http://dx.doi.org/10.1021/ja0200903 | zh_TW |
| dc.title | Selective Binding of Mannose-Encapsulated Gold Nanoparticles to Type I Pili in Escherichia Coli | en_US |