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The Acute Effects of Resistance Exercise on Cerebral Oxygenation and Excutive Control in Healthy Older Adults
|Abstract:||研究指出老化會減少腦部氧化血紅素和總血紅素，而引起認知與健康等問題，規律運動 可提升攝氧能力及減緩認知功能衰退。相較於有氧運動，阻力運動對於老年人腦氧合功能與 認知功能的相關研究較少。本研究之主要目的在比較急性阻力運動前、運動後立即和運動後 30分老年人腦氧合功能和認知執行控制的差異，並探討急性阻力運動後不同時間腦氧化功能 和執行控制能力之相關。本研究以30位65至75歲健康男性為對象，從事單次阻力訓練，內容 包括八個肌肉群，運動強度為70% 10RM(最大反覆次數)，每個動作10次，從事兩個回合。每 位受試者到實驗室五次,每次間隔至少三天, 前兩次為適應阻力訓練和預測各肌肉群的1RM, 最後三次則隨機分配至安靜(休息控制組)和兩次單次阻力訓練。於運動前、運動後立即及運 動後三十分鐘以近紅外線光譜儀(Near Infrared Spectroscopy, NIRS)測量腦部氧化能力(氧 和血紅素、去氧血紅素和總血紅素)，並分別以Sternberg task測量工作記憶能力和聽覺 Go-NO-Go測量執行功能。所得資料以重複量數二因子分析比較運動前後各相依變項的差異， 期望研究結果能提供運動保健參考。|
Previous research indicated that ageing decreased oxygenated hemoglobin and total hemoglobin in cerebral blood, resulting in cognitive and health dysfunction, while regular exercises could enhance the efficiency of oxygen utilization and alleviate cognitive decline. In comparison to aerobic exercise, there are fewer researches about effects of resistance exercise on cerebral oxygenation and cognitive functions of elderly. Therefore, the purpose of this study is to compare the differences of cerebral oxygenation and executive control in elderly people before, immediately after and thirty-minute-after acute resistance exercise. We would also like to examine whether there is any relationship between cerebral oxygenation and executive control in various time points. Thirty healthy males, aged from 65-75 years old, are to be recruited in this research and to engage in single-bout acute resistance training, which consists of 70%10RM, 10 repetitions per set, two sets per exercise in eight major muscle groups. All the subjects are asked to visit the lab for 5 times and separated at least 3 days each time. The first 2 times are arranged for 1 RM predictions of each muscle groups and muscle adaptation, and the other 3 times are randomly assigned for seated condition (rest control) and 2 acute resistance exercises. Near Infrared Spectroscopy (NIRS) is used to measure cerebral oxygenation, including oxygenated hemoglobin, deoxygenated hemoglobin and total hemoglobin. Sternberg task and Auditory Go-No-Go are used to measure working memory and executive control. Repeated-Measure Two Way ANOVA is used to analyze the differences in various dependent variables. We expect to use any possible research results as reference for exercise prescription for elderly people.
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