dc.contributor.author姜宏哲zh_tw
dc.date.accessioned2014-10-27T15:22:55Z
dc.date.available2014-10-27T15:22:55Z
dc.date.issued1990-06-??zh_TW
dc.description.abstract一些波菲林、金屬波菲林及有機鍺化合物顯示抗癌作用。因此本研究合成了5種新的鍺-四(甲基)波菲林衍生物(2~6),期能在抗癌療效上有幫助。四(甲基)波菲林(1)是由?咯和乙醛反應環成。1與四氯化鍺反應,得二氯一鍺一四(甲基)波菲林(2)。將2與礬土搖振得二羥基一鍺一四(甲基)波菲林 (3);與溴化乙基鎂反應得二乙基一鍺一四(甲基)波菲林(4);與溴化苯基鎂反應得到二苯基一鍺一四(甲基)波菲林(5)。由3與對一硝基酚反應得二一(對硝基酚基)者一四(甲基)波菲林(6)。zh_tw
dc.description.abstractSome porphyoins, metaloporphyrins and orgnogermanium compounds have antitumor ef-fects. In this study five new germanium tetramethyl porphyrins (2-6) were synthesized. Tetramethyl porphyrin (1) is prepared from pyrrole and acetaldehyde. 1 is reacted with germanium tetrachloride give dichlorogermanium tetramethyl porphyrin (1). Hydrolysis of 2 with alumina give dihydroxy germanium tetramethyl porphrin(3). Reaction of 2 with ethylmag-nesium bromide give diethylgermanium tetramethyl prophyrin(4); reaction with phenylgerma-nium bromide give diphenylgermanium tetramethyl porphyrin(5). Treatment of 3 with 4-nitrophenol give di-(4-nitrophenoxy) germanium tetramethyl porphyrin (6).en_US
dc.identifier1112B214-0BAF-56B3-CB29-41EDDD37423Azh_TW
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw/handle/20.500.12235/16894
dc.language中文zh_TW
dc.publisher國立臺灣師範大學研究發展處zh_tw
dc.publisherOffice of Research and Developmenten_US
dc.relation(35),217-227zh_TW
dc.relation.ispartof師大學報zh_tw
dc.subject.other四甲基波菲林zh_tw
dc.subject.other合成zh_tw
dc.subject.other衍生物zh_tw
dc.subject.otherzh_tw
dc.titlezh-tw
dc.title.alternativeSynthesis of Germanium Tetramethyl Porphyrinszh_tw

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