2'-去氧-5-氟脲核苷(抗腫瘤藥物)之合成法研討

dc.contributor.author姜宏哲zh_tw
dc.contributor.author王佩蓮zh_tw
dc.date.accessioned2014-10-27T15:26:13Z
dc.date.available2014-10-27T15:26:13Z
dc.date.issued1981-06-??zh_TW
dc.description.abstractThe synthetic methods of 2'-deoxy-5-fluorouridine (an antitumor drug) reported in-literature were extensively reviewed and discussed.The most economical synthetic route is the method modifide by Brown(5) 2', 3', 5'-Tri-O-acetyluridine was allowed to react with acetic acid containing fluorine. The reaction mixture was treated with ammonia in methyl alcohol to give 5-fluououridine. which was then deoxygenated to give the 2'-deoxy-5-fluorouridinein the overall yield 71%.en_US
dc.identifierD2E609D5-F4B8-2C25-A6FD-8C00269ACEA8zh_TW
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw/handle/20.500.12235/17704
dc.language中文zh_TW
dc.publisher國立臺灣師範大學研究發展處zh_tw
dc.publisherOffice of Research and Developmenten_US
dc.relation(26),465-480zh_TW
dc.relation.ispartof師大學報zh_tw
dc.subject.other合成法zh_tw
dc.subject.other抗腫瘤藥物zh_tw
dc.title2'-去氧-5-氟脲核苷(抗腫瘤藥物)之合成法研討zh-tw

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