Synthesis of 5, 5-Bis(p-methoxy- m -bromophenyl)-2-thiohydantoin Derivatives
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Date
1984-06-??
Authors
姜宏哲
王佩蓮
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Journal ISSN
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Publisher
國立臺灣師範大學研究發展處
Office of Research and Development
Office of Research and Development
Abstract
取5.5－雙（對甲氧－間溴苯基）－2－硫代乙內醯?（2a），點化甲烷，氫氧化鈉、乙醇、混合加熱，冷?可得到5.5－雙（對甲氧－間溴苯基）－2－甲基硫代乙內醯?（3a），產率81.0％，同樣的方法可合成（b3），（4a-4e）10個衍生物。
Treatment of 5,5-bis (p-methoxy-m-bromophenyl)-2-thiohydantoin (2a) with methyl iodide in basic alcohol solution gave 5,5-bis (p-methoxy-m-bromo-phenyl)-2-methythiohydantoin (3a), in 81.0% yield, whose ten new derivatives (3b-3f), (4a-4e) were also prepared in a similar fashion.
Treatment of 5,5-bis (p-methoxy-m-bromophenyl)-2-thiohydantoin (2a) with methyl iodide in basic alcohol solution gave 5,5-bis (p-methoxy-m-bromo-phenyl)-2-methythiohydantoin (3a), in 81.0% yield, whose ten new derivatives (3b-3f), (4a-4e) were also prepared in a similar fashion.