N ﹣甲基﹣甲硫基秋水仙的葡萄糖與甘露糖衍生物之合成

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dc.contributor.author廖焜熙zh_tw
dc.contributor.author蕭次融zh_tw
dc.date.accessioned2014-10-27T15:26:25Z
dc.date.available2014-10-27T15:26:25Z
dc.date.issued1990-06-??zh_TW
dc.description.abstract秋水仙素經五步驟反應合成了N-甲基-N-去乙醯-甲硫基秋水仙，為增強其水溶性，取該化合物與葡萄糖及甘露糖反應，合成了新化合物：N-甲基 -N-（D-葡糖基）-N-去乙醯-甲硫基秋水仙(7)及N-甲基-N-（D-甘露糖基）-N-去乙醯-甲硫基秋水仙(8)；將此兩化合物乙醯化，得到了 N-甲基-（四-氧-乙醯基-D-葡糖基）-N-去乙醯-甲硫基秋水仙(9)及N-甲基-N-（四-氧-乙醯基-D-甘露糖基）-N-去乙醯-甲硫基秋水仙(10)，以NMR分析其結構，其生理活性尚待試驗。zh_tw
dc.description.abstractFour new glycosyl derivatives 7-10 of N-methyl-methylthiocblchicine have been prepared from colchicine through an intermediate N-methyl-N-deacetyl-methylthiocolchicine (6) and ex-amined by NMR and MS techniques. The water solubility of new compounds is increased due to the glycosyl mioety.en_US
dc.identifierDF7B5734-82CC-F64E-E301-CC6236FC9529zh_TW
dc.identifier.urihttp://rportal.lib.ntnu.edu.tw/handle/20.500.12235/17767
dc.language中文zh_TW
dc.publisher國立臺灣師範大學研究發展處zh_tw
dc.publisherOffice of Research and Developmenten_US
dc.relation(35)，241-248zh_TW
dc.relation.ispartof師大學報zh_tw
dc.subject.other甘露糖zh_tw
dc.subject.other甲基zh_tw
dc.subject.other甲硫基秋水仙zh_tw
dc.subject.other合成zh_tw
dc.subject.other衍生物zh_tw
dc.subject.other葡萄糖zh_tw
dc.titleN ﹣甲基﹣甲硫基秋水仙的葡萄糖與甘露糖衍生物之合成zh-tw
dc.title.alternativeSynthesis of Glucosyl and Mannosyl Derivatives of N-Methylmethylhiocolghicinezh_tw

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