姚清發Yao, Ching-Fa簡弘聖Chien, Hung-Sheng2023-12-082023-07-282023-12-082023https://etds.lib.ntnu.edu.tw/thesis/detail/86612e920e730546096d4fafc146db0a/http://rportal.lib.ntnu.edu.tw/handle/20.500.12235/120983本篇論文首先回顧了關於咔唑(Carbazole)及其衍生物的合成和應用，接著是報導了我們所開發出的咔唑化合物合成策略以及結論的資訊。我們的合成策略是使用碘當為路易斯酸的催化條件下，將吲哚(Indole)和4-羰基-2,4-二苯基丁醛(4-Oxo-2,4-diphenylbutanal)進行兩次的親電芳香取代(SEAr)反應，反應機構推測會經過幾次的消去反應後並進行苯環化，而成功的合成出咔唑產物。This thesis reviews the synthesis and application of Carbazole and its derivatives at the beginning, followed by the synthesis strategy and conclusion of Carbazole compounds developed by us. The synthesis strategy we use is to use iodine as the catalytic condition of Lewis acid, indole will undergo two electrophilic aromatic substitution reactions on 4-Oxo-2,4-diphenylbutanal, And, it is speculated that there will be two elimination reactions to achieve Benzannulation, and finally the carbazole product is successfully synthesized.咔唑碘親電芳香取代反應消去反應苯環化CarbazoleIodineElectrophilic Aromatic substitutionElimination reactionBenzannulationetd