吳學亮Wu, Hsyueh-Liang梁書晨LIANG, Shu-Chen2019-09-04不公開2019-09-042019http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22G060642056S%22.&%22.id.&http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/100254本論文中主要探討利用一價銠金屬與掌性雙環[2.2.1]雙烯配基L5a所生成之掌性催化劑，催化芳香基硼酸試劑7對二烯炔之衍生物21進行不對稱骨牌環化反應(Enantioselective domino reaction)，生成具有兩個掌性中心之環化產物24，其中鏡像選擇性最高達到＞99.5%，產率最高達到92%。 預期利用合環產物24中環己二烯(Cyclohexadiene)之結構作為共軛雙烯體，與親二烯體(Dienophiles)進行狄耳士-阿德爾反應(Diels-Alder reaction)生成環加成產物63 以及環加成產物64。This thesis describes the enantioselective domino reaction of starting material 21 with arylboronic acid 7 in the presense of a Rh(I)-catalyst consisting chiral diene ligand L5a. The chiral adducts 24 were obtained in up to 92% yield and with up to >99.5% ee. The chiral 1,3-cyclohexadienes 24 was predicted with acylnitroso to afford cycloadducts 63 and 64.銠金屬催化掌性雙烯配基不對稱骨牌環化反應Rh(I)-catalystchiral diene ligandEnantioselective domino reaction