葉名倉Yeh, Ming-Chang林怡伶Lin, Yi-ling2020-12-142020-01-012020-12-142020http://etds.lib.ntnu.edu.tw/cgi-bin/gs32/gsweb.cgi?o=dstdcdr&s=id=%22G060742067S%22.&http://rportal.lib.ntnu.edu.tw:80/handle/20.500.12235/111163本篇論文將探討有效率合成3,4ｰ二取代吡咯的方法。在氮氣下，以甲苯為溶劑，使用C-2帶有炔醯胺側鏈的呋喃化合物，加入催化量的三氯化金進行反應，可快速得到吡咯衍生物，此吡咯衍生物帶有順式共軛烯酮的取代基，具有進行衍生反應的潛在能力。本反應的優點為溫和的反應條件、時間短及良好的產率。An efficient synthesis of 3,4ｰdisubstituted pyrroles is developed. Treatment of a catalytic amount of gold(III) chloride with furans tethering a ynamide at the C-2 position in toluene under nitrogen proceeds rapidly to afford pyrrole derivatives in good yields. The product possesses a (Z)-butenonyl side chain. The functionality may lead to further transformation. The advantages of this reaction are mild reaction conditions, short reaction times, and good yields.路易斯酸三氯化金吡咯炔醯胺金催化Lewis acidgold(III) chloridepyrroleynamidegold-catalyzed