Please use this identifier to cite or link to this item:
|Title:||Effect of intestinal production of equol on menopausal symptoms in women treated with soy isoflavones|
Jou HJ, Wu SC, Chang FW, Ling PY, Chu KS, Wu WH*
|Abstract:||Objective:To evaluate the effect of soy isoflavones on menopausal symptoms in women who do and who do not produce equol, a daidzein metabolite. Method:A randomized, double-blind, placebo-controlled clinical trial was conducted over 6 months with 96 healthy menopausal women. After taking take 135 mg of isoflavones daily for 1 week, the women in the study group were assigned to the equol-producing (EP) or the non-EP group according to the presence or absence of equol in their urine. Menopausal symptoms were evaluated using a modified Kupperman Index. Result:Compared with the placebo group, the scores for hot flashes and excessive sweating were significantly reduced after 3 months, and the scores for weakness, palpitations, limb paresthesia, and total symptoms after 6 months, in the EP group only. Conclusions:Isoflavone supplementation improves menopausal symptoms only in women with the ability to produce equol.|
|Appears in Collections:||教師著作|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.