Please use this identifier to cite or link to this item: http://rportal.lib.ntnu.edu.tw:80/handle/77345300/41313
Title: In vitro antimicrobial and anti-inflammatory effects of herbs against Propionibacterium acnes
Authors: 國立臺灣師範大學人類發展與家庭學系
Tsai TH, Tsai TH, Wu WH, Tseng TP, Tsai PJ
Issue Date: 1-Apr-2010
Publisher: Elsevier
Abstract: Propionibacterium acnes play an important role in the pathogenesis of acne by inducing certain inflammatory mediators and comedogenesis. The objective of this study was to evaluate the antimicrobial and anti-inflammatory effects of herbal extracts against P. acnes. Among the ten tested herbs, methanolic extracts of rose (Rosa damascene), duzhong (Eucommia ulmoides Oliv.), and yerba mate (Ilex paraguariensis) were found to inhibit the growth of P. acnes with respective minimum inhibitory concentrations of 2, 0.5, and 1 mg/ml. In addition, duzhong and yerba mate extracts reduced the secretion of pro-inflammatory cytokines such as tumour necrosis factor-α, interleukin (IL)-8, and IL-1β by human monocytic THP-1 cells pretreated with heat-killed P. acnes at a concentration of 0.1 mg/ml. Our results suggested that duzhong and yerba mate extracts possess both antimicrobial and anti-inflammatory effects against P. acnes and can possibly be used as therapeutic agents for acne.
URI: http://rportal.lib.ntnu.edu.tw/handle/77345300/41313
ISSN: 0308-8146
Other Identifiers: ntnulib_tp_A0305_01_003
Appears in Collections:教師著作

Files in This Item:
File SizeFormat 
ntnulib_tp_A0305_01_003.pdf252.57 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.